Clinical significance of D-dimer levels in refractory Mycoplasma pneumoniae pneumonia

Abstract Background The levels of serum D-dimer (D-D) in children with Mycoplasma pneumoniae pneumonia (MPP) were assessed to explore the clinical significance D-D refractory MPP (RMPP). Method A total 430 patients enrolled between January 2015 and December divided into a general (GMPP) group ( n = 306) RMPP 124). Clinical data, level, white blood cell (WBC) count, proportion neutrophils (N%), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), alanine transaminase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH) compared two groups. Multivariate logistic regression was performed identify independent predictors RMPP. Results (1) Hospitalization time, preadmission fever duration, WBC, N %, CRP, LDH, ESR, ALT, AST, significantly higher than those GMPP (all P < 0.05). (2) Correlation analysis showed that positively correlated could be used jointly evaluate severity disease. (3) identified LDH DD as risk factors for 0. 05). had highest predictive power 0.01). level also good ability predict pleural effusion liver injury Conclusion Serum increased RMPP, indicating excessive inflammatory response vascular endothelial prolonged duration existed this patient population. Increased may an early predictor occurrence complications. Our findings provide theoretical basis diagnosis intervention pathogenesis mycoplasma.